LSU defeated Oklahoma 37-17 in Week 14, with the Tigers' defense proving decisive in the second half. Oklahoma scored all 17 of its points in the first two quarters—7 in the first and 10 in the second—before being held scoreless over the final 30 minutes. LSU's offensive production came throughout the game, with the Tigers scoring 7 in the first quarter, 17 in the second, 7 in the third, and 6 in the fourth.

LSU's passing attack was led by AJ Swann, while receiver Chris Hilton Jr. recorded 85 yards receiving and scored a touchdown on a 45-yard pass from Garrett Nussmeier in the third quarter. Rusher Caden Durham added 80 yards on the ground. A critical third-quarter interception by Sage Ryan off Oklahoma's Bauer Sharp shifted momentum decisively in LSU's favor. The victory covered the 6-point spread and pushed the total over the 48-point line, with the game featuring 14 lead changes and a maximum win probability swing of 46.6 percent.