Oklahoma defeated Alabama 24-3 in Week 13, with the Sooners controlling the game after a slow first quarter. Alabama managed only a field goal in the opening period, while Oklahoma built momentum with 10 points in the second quarter before extending their lead with 14 points in the third.

The decisive moment came in the third quarter when Oklahoma's Kip Lewis returned an interception 49 yards for a touchdown, a play that swung momentum decisively in the Sooners' favor. Alabama's offense struggled throughout, with key mistakes including a Taylor Tatum fumble in the first quarter that was recovered by Alabama's Deontae Lawson.

Oklahoma's offense executed consistently, with Jackson Arnold completing 68 passing yards. Taylor Tatum led Oklahoma's rushing attack with 8 carries, while wide receiver Brenen Thompson contributed a 19-yard reception in the second quarter. For Alabama, Richard Young led receivers with 7 receptions.

The victory was decisive, with Oklahoma covering the 13.5-point spread. The game finished well under the over-under at 46.5 points, highlighting the Sooners' defensive dominance throughout the contest.